Turmeric rhizome Create Joint Pain

Wednesday, November 18, 2009

Osteoarthritis (OA) is a joint disease that results from joint cartilage degeneration, changes in bone and peradangandi in subkondral joints. This disease arises due to the aging condition and the trauma. Symptoms are often felt that the existence of rheumatic complaints in old age.

The disease is most common in the community because it is a major cause of musculoskeletal disorders throughout the world and the cause of the second largest disability after heart disease for age above 50 years.

WHO estimates that 400 per thousand of the world's population over the age of 70 years suffer from osteoarthritis and 800 per thousand patients (OA) has limited motion both mild to severe that reduce the quality of their lives. Osteoarthritis is the whole world with the prevalence of less than 50 people per thousand inhabitants in the population under the age of 45 years.

The most common joints affected joint osteoarthritis is a heavy buffer badab like the knee joint and hip joint. In general, clinical symptoms appear with joint pain on exertion, joint pains at night, stiff joints and sometimes there is swelling of the affected joints.

"Giving kurkuminoid turmeric rhizome extract reduces joint pain osteoarthritis stricken with skills no different than drugs that contain sodium diklofenak," said dr. Nyoman Kertia, Sp-PD as an open test at the Faculty of Medicine (FK) University of Gadjah Mada (UGM, in Bulaksumur, Yogyakarta, Wednesday (29/7/2009).

According to Nyoman, kurkuminoid can inhibit the enzyme secretion siklogenase-2 (COX-2) and Reactive Oxygen Intermediate (ROI), reducing levels of leukocytes and MDA sinovia fluid that can cause OA.

While anti-inflammatory drugs most prescribed by doctors around the world especially for the treatment of disorders caused muskiloskeletal OA. "This kind of medicine can only suppress inflammation and pain but not able to inhibit the OA disease progression," said faculty Medicine Section was.

Nyoman said there were some anti-inflammatory drugs needed to suppress the clinical symptoms of OA, but it is toxic to kondrosit thus worsening the disease itself. In general, side effects are quite a lot, especially the gastrointestinal tract, may interfere with liver function, kidney,
bone marrow and the cardiovascular system.

"It will increase costs and reduce quality of life of these patients," he said.

According to him, OA patients generally require treatment throughout their lives, especially anti-inflammatory drugs. Because there is no medicine that can cure chronic disease takes place. Kurkumoid are secondary metabolites found in the rhizome of turmeric and ginger, the kind that have been used saffron as a spice in the community and herbal components.

"Khasiatnya varied so it can be used to treat various diseases including rheumatic diseases," said the man born Buleleng, September 16, 1960.

Meanwhile, anti-inflammatory activity kurkumin he said, through three lines of pressing siklosigenase enzyme activity, enzyme lipoksigenase and as an antidote to free radicals. "Kurkumin ability is very very important, because two of the most played track in the process of joint inflammation is siklosigenase lines and free radical activity," he said.